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WAY 163909

Names

[ CAS No. ]:
428868-32-0

[ Name ]:
WAY 163909

[Synonym ]:
8H-Cyclopenta[b][1,4]diazepino[6,7,1-hi]indole, 1,2,3,4,7b,9,10,10a-octahydro-, (7bR,10aR)-
(7bR,10aR)-1,2,3,4,8,9,10,10a-Octahydro-7bH-cyclopenta[b][1,4]diazepino[6,7,1-hi]indole
ps-kr-n0
WAY 163909

Biological Activity

[Description]:

WAY 163909 is a potent and selective 5-HT(2C) receptor agonist with a Ki of 10.5±1.1 nM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Research Areas >> Cancer

[Target]

5-HT2C Receptor:10.5±1.1 nM (Ki)


[References]

[1]. Dunlop J1,WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity. J Pharmacol Exp Ther. 2005 May; 313(2):862-9. Epub 2005 Feb 10.


[Related Small Molecules]

Harmine | Pimavanserin | Serotonin hydrochloride | Sodium Ferulate | Thioridazine hydrochloride | Brexpiprazole | Risperidone | TG6-10-1 | Cariprazine | Quetiapine | SERTINDOLE | Alprenolol hydrochloride | B-HT 920 | Ketanserin | Palonosetron hydrochloride

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
350.4±21.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H18N2

[ Molecular Weight ]:
214.306

[ Flash Point ]:
160.2±13.0 °C

[ Exact Mass ]:
214.147003

[ PSA ]:
15.27000

[ LogP ]:
2.11

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.645

Related Compounds

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