2,4-Dibromothiazole

Names

[ Name ]:
2,4-Dibromothiazole

[Synonym ]:
2,4-Dibromo-1,3-thiazole
2,4-Dibromothiazole
Thiazole, 2,4-dibromo-
MFCD01318994
2,4- Dibromo thiazole

Biological Activity

[Description]:

2,4-Dibromothiazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

2,4-二溴噻唑用作合成 Melithiazole C 的结构单元，采用高度 (E)-选择性的衍生 4-乙烯基噻唑和二烯侧链之间的交叉复分解。它还用作制备各种具有生物活性特性的 2,4-分布式噻唑衍生物的中间体，例如运动神经元存活 (SMN) 蛋白调节剂。

Chemical & Physical Properties

[ Density]:
2.3±0.1 g/cm3

[ Boiling Point ]:
242.8±13.0 °C at 760 mmHg

[ Melting Point ]:
80-84°C

[ Molecular Formula ]:
C₃HBr₂NS

[ Molecular Weight ]:
242.92

[ Flash Point ]:
100.6±19.8 °C

[ Exact Mass ]:
240.819626

[ PSA ]:
41.13000

[ LogP ]:
2.70

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.650

[ Storage condition ]:
Keep Cold

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

A concise total synthesis of melithiazole C.

Org. Lett. 9 , 3425, (2007)

A short and convergent synthesis of the myxobacterial antibiotic melithiazole C is described featuring a highly E-selective cross-metathesis as the key step.