4-Methyl-5-acetyl thiazole
Names
[ CAS No. ]:
38205-55-9
[ Name ]:
4-Methyl-5-acetyl thiazole
[Synonym ]:
5-Acetyl-4-methylthiazole
4-Methyl-5-acetyl-thiazol
1-(4-Methyl-1,3-thiazol-5-yl)ethanone
4-Methyl-5-acetyl thiazole
Ethanone, 1-(4-methyl-5-thiazolyl)-
5-Acetyl-4-methyl-thiazol
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
228.6±20.0 °C at 760 mmHg
[ Molecular Formula ]:
C6H7NOS
[ Molecular Weight ]:
141.191
[ Flash Point ]:
92.0±21.8 °C
[ Exact Mass ]:
141.024841
[ PSA ]:
58.20000
[ LogP ]:
0.35
[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.539
[ Storage condition ]:
2-8°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2934100090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
J. Chromatogr. A. 182(1) , 55-62, (1980)
A simple and rapid gas chromatographic method for the quantitation of chlormethiazole and two of its pharmacologically active metabolites, 5-acetyl-4-methylthiazole and 5-(1-hydroxyethyl)-4-methylthia...
The metabolism of clomethiazole in gerbils and the neuroprotective and sedative activity of the metabolites.Br. J. Pharmacol. 129(1) , 95-100, (2000)
A single dose of clomethiazole (600 micromol kg(-1) i.p.) has previously been shown to be neuroprotective in the gerbil model of global ischaemia. In gerbils, clomethiazole (600 micromol kg(-1)) injec...