Fluorescamine

Names

[ Name ]:
Fluorescamine

[Synonym ]:
4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3'-dione
MFCD00005928
Ro 20-7234
Spiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione,4-phenyl
Fluorescamine
Spiro[furan-2(3H),1'(3'H)-isobenzofuran]-3,3'-dione, 4-phenyl-
Spiro(furan-2(3H),1'(3'H)-isobenzofuran)-3,3'-dione, 4-phenyl-
4-Phenylspiro[furan-2(3H),1'-phthalan]-3,3'-dione
Fluram(R)
4-phenylspiro[furan-2(3H)
4-Phenylspiro[Furan-2(3H),1-Phthalan]-3,3-Dione
4'-Phenyl-3H,3'H-spiro[2-benzofuran-1,2'-furan]-3,3'-dione
1'-phthalan]-3,3'-dione
fluram
UNII:Y6859V58YW
EINECS 253-814-5
4-Phenylspiro[furan-2(3H),1'(3'H)isobenzofuran]-3,3'-dione
4-PHENYLSPIRO(FURAN-2(3H),1'(3'H)-ISOBENZOFURAN)-3,3'-DIONE
4-phenyl-spiro[furan-2,1'-isobenzofuran]-3,3'-dione

Biological Activity

[Description]:

Fluorescamine( Ro 20-7234) is a spiro compound that is not fluorescent itself, but reacts with primary amines to form highly fluorescent products. It hence has been used as a reagent for the detection of amines and peptides.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
550.3±50.0 °C at 760 mmHg

[ Melting Point ]:
153-157 °C(lit.)

[ Molecular Formula ]:
C₁₇H₁₀O₄

[ Molecular Weight ]:
278.259

[ Flash Point ]:
248.5±30.2 °C

[ Exact Mass ]:
278.057922

[ PSA ]:
52.60000

[ LogP ]:
2.95

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.687

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
acetonitrile: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S36/37-S33-S29-S26-S16-S9-S37/39

[ RIDADR ]:
UN 1090 3/PG 2

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway.

PLoS ONE 10 , e0133181, (2015)

Sterol response element binding protein (SREBP) is a key transcription factor in insulin and glucose metabolism. We previously demonstrated that elevated levels of membrane sphingomyelin (SM) were rel...

Expression of aryl hydrocarbon receptor 1 (AHR1), AHR1 nuclear translocator 1 (ARNT1) and CYP1 family monooxygenase mRNAs and their activity in chicken ovarian follicles following in vitro exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

Toxicol. Lett. 237 , 100-11, (2015)

The aim of this in vitro study was to determine the effect of TCDD and luteinizing hormone (LH) on mRNA expression of aryl hydrocarbon receptor 1 (AHR1), AHR1 nuclear translocator 1 (ARNT1), and the C...

Potentiating effect of graphene nanomaterials on aromatic environmental pollutant-induced cytochrome P450 1A expression in the topminnow fish hepatoma cell line PLHC-1.

Environ. Toxicol. 30 , 1192-204, (2015)

Graphene and its derivatives are an emerging class of carbon nanomaterial with great potential for a broad range of industrial and consumer applications. However, their increasing production and use i...