Decamethoxine

Decamethoxine (Septefril) is a cationic gemini surfactant. Decamethoxine exhibits strong bactericidal and fungicidal effects. Decamethoxine modifies the permeability of the microbial cell membrane, resulting in the destruction and death of diverse microorganisms[1][2].

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Anti-infection >> Bacterial

Decamethoxine (Septefril) has a wide spectrum of antimicrobial action on Gram-positive bacteria (Staphylococcus, Streptococcus, Pneumococcus), Gram-negative bacteria (Pseudomonoas, Neisseria gonorrhoeae, Chlamydia trachomatis), protozoa, dermatophyte, yeast-like fungi of Candida genus, and viruses[1]. Decamethoxine at a concentration of 10 µg/ml drastically reduces the adhesion of coryneform bacteria, Salmonella, Staphylococcus, and Escherichia [2].

[1]. Kovalchuk V, et al. Naturally Drug-Loaded Chitin: Isolation and Applications. Mar Drugs. 2019;17(10):574. Published 2019 Oct 10.

[2]. Nazarchuk OA, et al. The research of antimicrobial efficacy of antiseptics decamethoxin, miramistin and their effect on nuclear DNA fragmentation and epithelial cell cycle. Wiad Lek. 2019;72(3):374-380.