4-nitrophenyl α-D-glucoside

Names

[ Name ]:
4-nitrophenyl α-D-glucoside

[Synonym ]:
4-Nitrophenyl α-D-glucopyranoside
4-Nitrophenyl α-D-Glucopyranoside [Substrate
MFCD00064088
4-nitrophenyl α-D-glucoside
EINECS 223-189-3
α-D-Glucopyranoside, 4-nitrophenyl
4-Nitrophenyl a-D-glucopyranoside

Biological Activity

[Description]:

4-Nitrophenyl a-D-glucopyranoside is a chromogenic substrate for α-glucosidase. 4-Nitrophenyl a-D-glucopyranoside can be used to measure of α-glucosidase activity[1][2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

4-Nitrophenyl a-D-glucopyranoside 通过酶促裂解释放对硝基苯酚。4-Nitrophenyl a-D-glucopyranoside 可以通过 405 nm 的比色检测进行定量[2]。

[References]

[1]. Zeng L, et, al. Inhibitory mechanism of morin on α-glucosidase and its anti-glycation properties. Food Funct. 2016 Sep 14;7(9):3953-63.

[2]. Binder TP, et, al. p-Nitrophenyl alpha-D-glucopyranoside, a new substrate for glucansucrases. Carbohydr Res. 1983 Dec 23;124(2):287-99.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
582.2±50.0 °C at 760 mmHg

[ Melting Point ]:
210-216ºC

[ Molecular Formula ]:
C₁₂H₁₅NO₈

[ Molecular Weight ]:
301.249

[ Flash Point ]:
305.9±30.1 °C

[ Exact Mass ]:
301.079773

[ PSA ]:
145.20000

[ LogP ]:
-0.55

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.648

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Pregnane-type steroidal glycosides from Gymnema griffithii Craib.

Phytochemistry 106 , 197-206, (2014)

Eight pregnane-type steroidal glycosides substituted with ortho-acetate groups were isolated from the methanolic extract of the pericarp of Gymnema griffithii fruits, and named gymnemogriffithosides A...

Alpha-amylase Inhibition and Antioxidant Activity of Marine Green Algae and its Possible Role in Diabetes Management.

Pharmacogn. Mag. 11 , S511-5, (2016)

In the continuing search for safe and efficient antidiabetic drug, marine algae become important source which provide several compounds of immense therapeutic potential. Alpha-amylase, alpha-glucosida...

Selective α-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties.

Bioorg. Med. Chem. Lett. 21 , 2441-4, (2011)

We constructed a library of sugar-dipeptide conjugate to find out the best complementary against hydrophobic pocket of α-glucosidase. The best substrate showed 150-fold improved K(m) value relative p-...