Ethyl 4-pyrazolecarboxylate

Names

[ Name ]:
Ethyl 4-pyrazolecarboxylate

[Synonym ]:
Ethyl pyrazole-4-carboxylate
MFCD00010844
1H-Pyrazole-4-carboxylic acid, ethyl ester
Ethyl 4-Pyrazolecarboxylate
4-Pyrazolecarboxylic Acid Ethyl Ester
Ethyl 1H-pyrazole-4-carboxylate
Ethyl-1H-pyrazole-4-carboxylate

Biological Activity

[Description]:

4-Ethoxycarbonylpyrazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

1H-pyrazole-4-carboxylate 乙酯用于制备 isoxazole-4-carboxylic acid 衍生物和 isoxazole-3,5-dicarboxamides。此外，它还是有机合成的中间体。

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
307.8±0.0 °C at 760 mmHg

[ Melting Point ]:
78-80 °C(lit.)

[ Molecular Formula ]:
C₆H₈N₂O₂

[ Molecular Weight ]:
140.14

[ Flash Point ]:
122.7±19.8 °C

[ Exact Mass ]:
140.058578

[ PSA ]:
54.98000

[ LogP ]:
1.25

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.522

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Copper-diamine-catalyzed N-arylation of pyrroles, pyrazoles, indazoles, imidazoles, and triazoles.

J. Org. Chem. 69 , 5578, (2004)

This paper details the copper-catalyzed N-arylation of pi-excessive nitrogen heterocycles. The coupling of either aryl iodides or aryl bromides with common nitrogen heterocycles (pyrroles, pyrazoles, ...

Conversion of cysteinyl residues to unnatural amino acid analogs. Examination in a model system.

J. Protein Chem. 15(8) , 737-42, (1996)

Improved and efficient techniques have led to an explosive growth in the application of site-directed mutagenesis to the study of enzymes. However, the limited availability of only those 20 amino acid...