NBI 31772

Names

[ Name ]:
NBI 31772

[Synonym ]:
3-Isoquinolinecarboxylic acid,1-(3,4-dihydroxybenzoyl)-6,7-dihydroxy

Biological Activity

[Description]:

NBI-31772 is the potent and nonselective inhibitor of IGFBP with a Ki value of 47 nM. NBI-31772 has the potential for the research of IGF-responsive diseases[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R

[References]

[1]. Khawaja XZ. Development of a scintillation proximity assay for human insulin-like growth factor-binding protein 4 compatible with inhibitor high-throughput screening. Anal Biochem. 2007;366(1):80-86.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₁NO₇

[ Molecular Weight ]:
341.27200

[ Exact Mass ]:
341.05400

[ PSA ]:
147.92000

[ LogP ]:
0.85900

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Related Compounds

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