FR260010 free base

Names

[ CAS No. ]:
374555-75-6

[ Name ]:
FR260010 free base

[Synonym ]:
FR 260010
FR-260010

Biological Activity

[Description]:

FR260010 free base is a selective 5-HT2C receptor antagonist, with a Ki value of 1.1 nM[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

Ki: 1.1 nM (5-HT2C receptor)[1].

[References]

[1]. Katsuya Harada, et al. Activation of the serotonin 5-HT2C receptor is involved in the enhanced anxiety in rats after single-prolonged stress. Pharmacol Biochem Behav. 2008 Mar;89(1):11-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₉N₅

[ Molecular Weight ]:
353.43

Related Compounds

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