A201A

Names

[ Name ]:
A201A

[Synonym ]:
Antibiotic A 201A
A 201A

Biological Activity

[Description]:

A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Nie S, et al. Total synthesis of nucleoside antibiotic A201A. J Am Chem Soc. 2014 Mar 19;136(11):4157-60.

[2]. Wang J, et al. Bioinspired Total Synthesis of Complex Nucleoside Antibiotics A201A, A201D and A201E. Angew Chem Int Ed Engl. 2023 Jan 16;62(3):e202213810.

Chemical & Physical Properties

[ Density]:
1.52g/cm3

[ Molecular Formula ]:
C₃₇H₅₀N₆O₁₄

[ Molecular Weight ]:
802.82500

[ Exact Mass ]:
802.33900

[ PSA ]:
254.42000

[ LogP ]:
0.03870

[ Index of Refraction ]:
1.655