2,4-Difluoroaniline
Names
[ CAS No. ]:
367-25-9
[ Name ]:
2,4-Difluoroaniline
[Synonym ]:
2,4-difluorophenylamine
2,4-DIFLOUROANILINE
Benzenamine, 2,4-difluoro-
Difluoroaniline
4-Difluoroaniline
2,4-Difluoranilin
2,4-difluoro-anilin
2,4-difluorobenzenamine
2,4-difluorobenzeneamine
Aniline,2,4-difluoro
EINECS 206-687-5
2,4-Difluoroaniline
4-fluoro-2-fluoroaniline
MFCD00007648
2,4-Difluoro-aniline
2,4-DIFLUROANILINE
2,4,6-TRIFLUOROPHENYL ISOCYANATE
2,4-fluoroaniline
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
168.4±20.0 °C at 760 mmHg
[ Melting Point ]:
−7.5 °C(lit.)
[ Molecular Formula ]:
C6H5F2N
[ Molecular Weight ]:
129.107
[ Flash Point ]:
62.8±0.0 °C
[ Exact Mass ]:
129.039001
[ PSA ]:
26.02000
[ LogP ]:
1.52
[ Vapour Pressure ]:
1.6±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.521
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
[ Water Solubility ]:
1-5 g/100 mL at 20.55 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX3680000
- CHEMICAL NAME :
- Aniline, 2,4-difluoro-
- CAS REGISTRY NUMBER :
- 367-25-9
- BEILSTEIN REFERENCE NO. :
- 2802556
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C6-H5-F2-N
- MOLECULAR WEIGHT :
- 129.12
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 mg/plate
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H311-H331
[ Precautionary Statements ]:
P261-P280-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S28-S36/37/39-S26
[ RIDADR ]:
UN 2941 6.1/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
BX3680000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2921420090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Int. Arch. Occup. Environ. Health 54(3) , 223-32, (1984)
Two possible methods for monitoring exposure to 2,4-difluoroaniline and 4-fluoroaniline have been investigated: measurement of methaemoglobin content in blood and measurement of urinary metabolites. E...
Subacute toxicity assessment of water disinfection byproducts on zebrafish.Pathol. Oncol. Res. 18(3) , 579-84, (2012)
Disinfection of raw water is essential to the production of drinking water. However, by-products of disinfection may exert toxic effects. The potential toxic effects of two of these compounds, 4-ethyl...
High resolution NMR study of T1 magnetic relaxation dispersion. III. Influence of spin 1/2 hetero-nuclei on spin relaxation and polarization transfer among strongly coupled protons.J. Chem. Phys. 137(9) , 094503, (2012)
Effects of spin-spin interactions on the nuclear magnetic relaxation dispersion (NMRD) of protons were studied in a situation where spin ½ hetero-nuclei are present in the molecule. As in earlier work...