1,3-Difluorobenzene
Names
[ CAS No. ]:
372-18-9
[ Name ]:
1,3-Difluorobenzene
[Synonym ]:
1,3-difluroethylene
1-Difluorobenzene
MFCD00000327
3-DifluoroBenzene
meta-difluorobenzene
m-Difluorobenzene
m-Difluro Benzene
1,3 difluorobenzene
1,3-DIFLUOROBENZEN
FR CF
2,4-difluorobenzene
m-difluoro-benzen
2,6-difluorobenzene
Benzene,m-difluoro
Benzene, 1,3-difluoro-
1,3-Difluorobenzene
DIFLOUROBENZENE
1,3-Difluorbenzol
EINECS 206-746-5
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
83.9±13.0 °C at 760 mmHg
[ Melting Point ]:
-59 °C
[ Molecular Formula ]:
C6H4F2
[ Molecular Weight ]:
114.093
[ Flash Point ]:
2.2±0.0 °C
[ Exact Mass ]:
114.028107
[ LogP ]:
2.36
[ Vapour Pressure ]:
82.7±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.449
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ5652000
- CHEMICAL NAME :
- Benzene, m-difluoro-
- CAS REGISTRY NUMBER :
- 372-18-9
- LAST UPDATED :
- 199501
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H4-F2
- MOLECULAR WEIGHT :
- 114.10
- WISWESSER LINE NOTATION :
- FR CF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 gm/m3/2H
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS
- REFERENCE :
- IZSBAI Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. (Novosibirsk, USSR) No.1-3, 1963-68. For publisher information, see ISBNBN. Volume(issue)/page/year: 3,91,1965
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H332
[ Precautionary Statements ]:
P210
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F:Flammable
[ Risk Phrases ]:
R11;R20
[ Safety Phrases ]:
S7-S16-S29-S33
[ RIDADR ]:
UN 1993 3/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
CZ5652000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
29036990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903999090
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
J. Org. Chem. 71(5) , 2170-2, (2006)
A short, high-yielding synthesis of differentially substituted resorcinol derivatives has been developed that utilizes 1,3-difluorobenzene as the starting material and employs sequential nucleophilic ...
Decomposition of alpha-hydroxyaryl ketones and characterization of some unusual products.J. Pharm. Sci. 81(12) , 1199-203, (1992)
Alpha-Hydroxyaryl ketones such as 2-hydroxypropiophenone and 1-(2,4-difluorophenyl)-2-hydroxy-1-propanone, the key intermediates in the preparation of antifungal agents, decompose into oxidized, rearr...