1,2-Difluorobenzene
Names
[ CAS No. ]:
367-11-3
[ Name ]:
1,2-Difluorobenzene
[Synonym ]:
ortho-difluorobenzene
Isoamylamine
o-Difluorobenzene
2-Difluorobenzene
o-difluoro-benzen
1,2-Difluorobenzene
EINECS 206-680-7
Benzene,o-difluoro
1,2-difluroethylene
1,2-difluoro-benzene
FR BF
difluorobenzene
1,2-Difluorbenzol
MFCD00000284
1,2-diflurobenzene
Benzene, 1,2-difluoro-
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
93.3±13.0 °C at 760 mmHg
[ Melting Point ]:
−34 °C(lit.)
[ Molecular Formula ]:
C6H4F2
[ Molecular Weight ]:
114.093
[ Flash Point ]:
2.2±0.0 °C
[ Exact Mass ]:
114.028107
[ LogP ]:
2.23
[ Vapour Pressure ]:
56.6±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.449
[ Stability ]:
Stable. Incompatible with strong oxidizing agents. Highly flammable. Note low flash point.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ5655000
- CHEMICAL NAME :
- Benzene, o-difluoro-
- CAS REGISTRY NUMBER :
- 367-11-3
- BEILSTEIN REFERENCE NO. :
- 1905113
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H4-F2
- MOLECULAR WEIGHT :
- 114.10
- WISWESSER LINE NOTATION :
- FR BF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 gm/m3/2H
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- IZSBAI Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. (Novosibirsk, USSR) No.1-3, 1963-68. For publisher information, see ISBNBN. Volume(issue)/page/year: 3,91,1965
Safety Information
[ Symbol ]:
GHS02
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225
[ Precautionary Statements ]:
P210
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F:Flammable
[ Risk Phrases ]:
R11;R20
[ Safety Phrases ]:
S7-S16-S29-S33
[ RIDADR ]:
UN 1993 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
CZ5655000
[ Packaging Group ]:
II
[ Hazard Class ]:
3
[ HS Code ]:
29036990
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903999090
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 107 , 1-7, (2013)
In this work, the structures and normal vibrations of p-difluorobenzene and ethylbenzene in the first excited state have been studied using resonant two-photon ionization spectrum and ab initio quantu...
Ionized o-, m-, and p-difluorobenzene dissociate through ring-opened intermediates: a TPEPICO investigation.J. Am. Soc. Mass Spectrom. 20(1) , 20-4, (2009)
Threshold photoelectron photoion coincidence (TPEPICO) experiments have shown that o-, m-, and p-difluorobenzene ions dissociate via a common, ring-opened intermediate and not via ionized p-difluorobe...
Regioselectivity of cytochrome P-450 catalyzed hydroxylation of fluorobenzenes predicted by calculated frontier orbital substrate characteristics.Biochemistry 32(18) , 4801-12, (1993)
In the present study, a hypothesis is presented for the prediction of the regioselectivity of cytochrome P-450 catalyzed hydroxylation of fluorobenzenes. The regioselectivity of the in vivo hydroxylat...