tert-Butyl hydroxycarbamate

Names

[ Name ]:
tert-Butyl hydroxycarbamate

[Synonym ]:
(tert-butyl)oxycarbohydroxamic acid
N-(tert-Butoxycarbonyl)hydroxylamine
tert-butyl N-hydroxy-carbamate
N-tert-Butoxycarbonylhydroxylamine
MFCD00002107
tert-Butyl hydroxycarbamate
t-Butyl N-hydroxycarbamate
EINECS 252-836-2
N-Boc-hydroxylamine
1,1-dimethylethyl N-hydroxycarbamate
N-Hydroxycarbamic Acid tert-Butyl Ester
2-Methyl-2-propanyl hydroxycarbamate
N-(t-Butoxycarbonyl)-hydroxylamine
Carbamic acid, N-hydroxy-, 1,1-dimethylethyl ester

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
250.4±9.0 °C at 760 mmHg

[ Melting Point ]:
53-55 °C(lit.)

[ Molecular Formula ]:
C₅H₁₁NO₃

[ Molecular Weight ]:
133.146

[ Flash Point ]:
105.2±18.7 °C

[ Exact Mass ]:
133.073898

[ PSA ]:
58.56000

[ LogP ]:
0.82

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.443

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29280090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.

J. Med. Chem. 54 , 6843-58, (2011)

The discovery, syntheses, and structure-activity relationships (SAR) of a new family of heterocyclic antibacterial compounds based on N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds are described. A s...

Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase.

J. Med. Chem. 35 , 3648, (1992)

In the preceding paper, analogs of chlorpropamide with an OMe substituent on the sulfonamide nitrogen were shown to inhibit aldehyde dehydrogenase (AlDH), and it was postulated that these compounds we...

Reactions of nitroso hetero-Diels-Alder cycloadducts with azides: stereoselective formation of triazolines and aziridines.

J. Org. Chem. 72 , 3929, (2007)

The addition of azides to acylnitroso hetero-Diels-Alder cycloadducts derived from cyclopentadiene affords exo-triazolines in excellent yield. The reaction is greatly affected by the level of alkene s...