3-Oxo-4-(?D-ribofuranosyl)-3,4-dihydro-2-pyrazinecarboxamide

Names

[ Name ]:
3-Oxo-4-(?D-ribofuranosyl)-3,4-dihydro-2-pyrazinecarboxamide

Biological Activity

[Description]:

3,4-Dihydro-3-oxo-4-β-D-ribofuranosyl-2-pyrazinecarboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₃N₃O₆

[ Molecular Weight ]:
271.23