1-Fluoro-4-nitrobenzene
Names
[ CAS No. ]:
350-46-9
[ Name ]:
1-Fluoro-4-nitrobenzene
[Synonym ]:
4-nitro-1-fluorobenzene
MFCD00007282
1-Fluoro-4-nitrobenzene
4-fluoro-nitro-benzene
Benzene, o-nitrofluoro-
Fluoronitrobenzene3
P-FLUORONITROBENZENE
o-nitrofluorobenzene
4-fluoro-1-nitrobenzene
Benzene, 1-fluoro-4-nitro-
Benzene, 1-fluoro-2-nitro-
WNR BF
p-fluoronitorobenzene
p-fluoromitrobenzene
4-Fluornitrobenzol
EINECS 206-502-8
para-fluoronitrobenzene
1-Fluor-4-nitrobenzol
1-Fluoro-2-nitrobenzene
P-NITROFLUOROBENZENE
2-Nitrofluorobenzene
para-nitro fluorobenzene
4-NITROFLUOROBENZENE
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
206.5±0.0 °C at 760 mmHg
[ Melting Point ]:
21 °C(lit.)
[ Molecular Formula ]:
C6H4FNO2
[ Molecular Weight ]:
141.100
[ Flash Point ]:
83.3±0.0 °C
[ Exact Mass ]:
141.022614
[ PSA ]:
45.82000
[ LogP ]:
1.80
[ Vapour density ]:
>1 (vs air)
[ Vapour Pressure ]:
0.3±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.534
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DA1400000
- CHEMICAL NAME :
- Benzene, 1-fluoro-4-nitro-
- CAS REGISTRY NUMBER :
- 350-46-9
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C6-H4-F-N-O2
- MOLECULAR WEIGHT :
- 141.11
- WISWESSER LINE NOTATION :
- WNR DF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 160 nL/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,217,1983
Safety Information
[ Symbol ]:
GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H312-H331-H373
[ Precautionary Statements ]:
P261-P280-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S36-S36/37
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
DA1400000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
29049085
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2904909090
[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Biochem. J. 294 ( Pt 3) , 653-6, (1993)
Michaelis-Menten parameters for hydrolysis of seven aryl N-acetyl alpha-D-neuraminides by Vibrio cholerae neuraminidase at pH 5.0 correlate well with the leaving-group pKa (delta pK 3.0; beta 1g (V/K)...
f-[18F]fluoroethanol and 3-[18F]fluoropropanol: facile preparation, biodistribution in mice, and their application as nucleophiles in the synthesis of [18F]fluoroalkyl aryl ester and ether PET tracers.Nucl. Med. Biol. 40(6) , 850-7, (2013)
2-[(18)F]Fluoroethoxy and 3-[(18)F]fluoropropoxy groups are common moieties in the structures of radiotracers used with positron emission tomography. The objectives of this study were (1) to develop a...
A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages.Chem. Biol. 14(11) , 1221-31, (2007)
The myeloperoxidase (MPO)-derived oxidant hypochlorous acid (HOCl/OCl(-)) is implicated in the pathogenesis of atherosclerosis and other inflammatory states. We have synthesized an imaging probe, sulf...