3-Chloro-4-fluoronitrobenzene

Names

[ CAS No. ]:
350-30-1

[ Name ]:
3-Chloro-4-fluoronitrobenzene

[Synonym ]:
3-chloro-4-fluoro-1-nitrobenzene
3-Chloro-4-fluoronitrobenzene
1-chloro-2-fluoro-5-nitrobenzene
2-Chloro-1-fluoro-4-nitrobenzene
1-fluoro-2-chloro-4-nitrobenzene
2-chloro-1-fluoro-4-nitro-benzen
3-Chloro-4-fluoronit
4-FLUORO-3-CHLORONITROBENZENE
3-chloro-4-fluoro-nitrobenzene
EINECS 206-499-3
Benzene, 2-chloro-1-fluoro-4-nitro-
WNR CG DF
3-CHLORO-4-FLUORONITROANILINE
1-Nitro-3-chloro-4-fluorobenzene
MFCD00007206
3-chloro-4-fluorobenzene

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
232.5±20.0 °C at 760 mmHg

[ Melting Point ]:
40-42 °C(lit.)

[ Molecular Formula ]:
C₆H₃ClFNO₂

[ Molecular Weight ]:
175.545

[ Flash Point ]:
94.4±21.8 °C

[ Exact Mass ]:
174.983627

[ PSA ]:
45.82000

[ LogP ]:
2.60

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.555

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ0720000

CHEMICAL NAME :: Benzene, 2-chloro-1-fluoro-4-nitro-

CAS REGISTRY NUMBER :: 350-30-1

BEILSTEIN REFERENCE NO. :: 1944997

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H3-Cl-F-N-O2

MOLECULAR WEIGHT :: 175.55

WISWESSER LINE NOTATION :: WNR CG DF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 102 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 116,217,1983

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S39-S36/37/39

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
CZ0720000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2904909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2904909090

[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Microwave mediated reduction of heterocycle and fluorine containing nitroaromatics with Mo (CO)₆ and DBU. Spencer J, et al.

Tetrahedron 64(44) , 10195-10200, (2008)

Microwave-assisted traceless synthesis of benzimidazolones. Xu X-J and Zong Y-X.

Tetrahedron Lett. 48(1) , 129-32, (2007)

Practical and efficient synthesis of N-fused tricyclic indoles. Koay N, et al.

Tetrahedron Lett. 52(1) , 122-4, (2011)