6-Chloro-L-tryptophan

Names

[ CAS No. ]:
33468-35-8

[ Name ]:
6-Chloro-L-tryptophan

[Synonym ]:
6-Chloro-L-tryptophan
L-Tryptophan, 6-chloro-

Biological Activity

[Description]:

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

6-Chloro-L-tryptophan (0-500 μM) exhibits no inhibitory effect on D-amino acid oxidase (DAO)[2].

[References]

[1]. Heemstra JR Jr, et al. Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly. J Am Chem Soc. 2008 Oct 29;130(43):14024-5.

[2]. Iwasaki M, et al. A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity. Biomed Chromatogr. 2016 Mar;30(3):384-9.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
476.9±45.0 °C at 760 mmHg

[ Melting Point ]:
244-246ºC

[ Molecular Formula ]:
C₁₁H₁₁ClN₂O₂

[ Molecular Weight ]:
238.670

[ Flash Point ]:
242.2±28.7 °C

[ Exact Mass ]:
238.050903

[ PSA ]:
79.11000

[ LogP ]:
1.63

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.702

[ Storage condition ]:
-20°C Freezer

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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