6-Chloro-1H-indole
Names
[ CAS No. ]:
17422-33-2
[ Name ]:
6-Chloro-1H-indole
[Synonym ]:
6-chloro indole
1H-Indole, 6-chloro-
MFCD00005681
6-Chloroindole
6-Cl-indole
EINECS 241-449-4
1H-Indole,6-chloro
6-chlorolindole
6-Chloro-1H-indole
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
293.0±13.0 °C at 760 mmHg
[ Melting Point ]:
87-90 °C(lit.)
[ Molecular Formula ]:
C8H6ClN
[ Molecular Weight ]:
151.59
[ Flash Point ]:
158.9±5.4 °C
[ Exact Mass ]:
151.018875
[ PSA ]:
15.79000
[ LogP ]:
2.74
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.688
[ Stability ]:
Store in Refrigerator
[ Water Solubility ]:
slightly soluble
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014)
Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatme...
Toward prediction of alkane/water partition coefficients.J. Med. Chem. 51 , 3720-30, (2008)
Partition coefficients were measured for 47 compounds in the hexadecane/water ( P hxd) and 1-octanol/water ( P oct) systems. Some types of hydrogen bond acceptor presented by these compounds to the pa...
Production of substituted L-tryptophans by fermentation.Appl. Microbiol. 21(5) , 841-3, (1971)
Claviceps purpurea has been shown to produce extracellular l-tryptophan from indole in stirred fermentors. The substrate specificity of this conversion was investigated by using substituted indoles, a...