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Tricin 7-O-glucoside

Names

[ CAS No. ]:
32769-01-0

[ Name ]:
Tricin 7-O-glucoside

[Synonym ]:
morifonoside A
5,4'-dihydroxy-3',5'-dimethoxy-7-O-β-D-glucopyranosylflavone
5-Hydroxy-2-(4-hydroxy-3,5-dimethoxy-phenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-chromen-4-one
4',5-dihydroxy-3',5'-dimethoxyflavone 7-O-β-D-glucoside
3',5'-dimethoxytricetin-7-O-β-D-glucopyranoside
tricin 7-O-β-D-glucopyranoside

Biological Activity

[Description]:

Tricin 7-O-β-D-glucopyranoside is a potent and orally active neuroprotective agent. Tricin 7-O-β-D-glucopyranoside induces Apoptosis. Tricin 7-O-β-D-glucopyranoside decreases the expression of TNF-α induced phosphor-κB-α, phosphor-NF-κB, HMGB1[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Neurological Disease

[References]

[1]. Jiang WL, et al. Tricin 7-glucoside protects against experimental cerebral ischemia by reduction of NF-κB and HMGB1 expression. Eur J Pharm Sci. 2012 Jan 23;45(1-2):50-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C23H24O12

[ Molecular Weight ]:
492.43

[ Exact Mass ]:
492.12700

[ PSA ]:
188.51000

[ LogP ]:
0.06710

Related Compounds