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Homoeriodictyol 7-O-glucoside

Names

[ CAS No. ]:
14982-11-7

[ Name ]:
Homoeriodictyol 7-O-glucoside

[Synonym ]:
Hedt-II
5-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-chroman-4-one
Homoeriodictyol-7-glucosid
homoeriodictyol-7-O-β-D-glucopyranoside

Biological Activity

[Description]:

Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others

[Target]

platelet-activating factor[1]


[In Vitro]

Homoeriodictyol 7-O-β-D-glucoside significantly inhibits human and rabbit platelet aggregation induced by PAF, but has no inhibitory effect on platelet aggregation induced by Adenosine diphosphate (ADP)[1].

[References]

[1]. Zengwei G, et, al. A novel platelet-activating factor antagonist isolated from a Chinese herbal drug Viscum coloratum.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H24O11

[ Molecular Weight ]:
464.41900

[ Exact Mass ]:
464.13200

[ PSA ]:
175.37000

Related Compounds