4-Nitroguaiacol

Names

[ Name ]:
4-Nitroguaiacol

[Synonym ]:
4-Hydroxy-3-methoxynitrobenzene
EINECS 221-839-0
2-Methoxy-4-nitrophenol
MFCD00012143
Phenol,o-methoxy-p-nitro
Mononitro guaiacol
3-Nitro-6-hydroxyanisole
4-nitro-2-methoxyphenol
Phenol,2-methoxy-4-nitro
o-Methoxy-p-nitrophenol
2-Methoxy-4-nitro-phenol
4-Nitroguaiacol
Guaiacol,4-nitro
2-Hydroxy-5-nitroanisole
Phenol, 2-methoxy-4-nitro-

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
335.2±27.0 °C at 760 mmHg

[ Melting Point ]:
102-104 °C(lit.)

[ Molecular Formula ]:
C₇H₇NO₄

[ Molecular Weight ]:
169.135

[ Flash Point ]:
156.5±23.7 °C

[ Exact Mass ]:
169.037506

[ PSA ]:
75.28000

[ LogP ]:
1.58

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.583

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL7800000

CHEMICAL NAME :: Phenol, 2-methoxy-4-nitro-

CAS REGISTRY NUMBER :: 3251-56-7

BEILSTEIN REFERENCE NO. :: 1868796

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H7-N-O4

MOLECULAR WEIGHT :: 169.15

WISWESSER LINE NOTATION :: WNR DQ CO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - other changes

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,221,1954

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
SL7800000

[ HS Code ]:
2909500000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2909500000

[ Summary ]:
2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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