3’-Azido-3’-deoxy-5-fluorouridine

Names

[ CAS No. ]:
307520-05-4

[ Name ]:
3’-Azido-3’-deoxy-5-fluorouridine

[Synonym ]:
3'-Azido-3'-deoxy-5-fluorouridine
Uridine, 3'-azido-3'-deoxy-5-fluoro-

Biological Activity

[Description]:

3’-Azido-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C9H10FN5O5

[ Molecular Weight ]:
287.20

[ Exact Mass ]:
287.066589

[ LogP ]:
-0.74

Related Compounds

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