S26131

Names

[ Name ]:
S26131

Biological Activity

[Description]:

S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Melatonin Receptor

Signaling Pathways >> GPCR/G Protein >> Melatonin Receptor

Research Areas >> Neurological Disease

[In Vitro]

S26131 behaves as an antagonist on MT1 and MT2 receptors with KB values of 5.32 and 143 nM, respectively[1].

[References]

[1]. Descamps-François C, et al. Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands. J Med Chem. 2003 Mar 27;46(7):1127-9.

Chemical & Physical Properties

[ Density]:
1.168±0.06 g/cm3(Predicted)

[ Boiling Point ]:
804.6±65.0 °C(Predicted)

[ Molecular Formula ]:
C₃₁H₃₄N₂O₄

[ Molecular Weight ]:
498.61

[ Storage condition ]:
2-8°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.