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(±)-Muscarine chloride

Names

[ CAS No. ]:
2936-25-6

[ Name ]:
(±)-Muscarine chloride

[Synonym ]:
(+/-)-muscarine chloride

Biological Activity

[Description]:

(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototype muscarinic acetylcholine receptor agonist[1][2].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR
Signaling Pathways >> GPCR/G Protein >> mAChR
Research Areas >> Neurological Disease

[In Vivo]

The sites activated by (±)-Muscarine chloride (injected into the cerebral ventricles of conscious cats) in the CNS producing aggressive behaviour have the following characteristics: in high doses muscarine acted on muscarinic cholinoceptive sites, while in small doses it activated the cholinoceptive sites having muscarinic and nicotinic characteristics[1].

[References]

[1]. Radu BM, et al. All muscarinic acetylcholine receptors (M1-M5) are expressed in murine brain microvascular endothelium. Sci Rep. 2017;7(1):5083. Published 2017 Jul 11.

[2]. Beleslin DB, et al. The pharmacology of aggressive behavioural phenomena elicited by muscarine injected into the cerebral ventricles of conscious cats. Psychopharmacology (Berl). 1979;60(2):155-158.

Chemical & Physical Properties

[ Melting Point ]:
180-181ºC

[ Molecular Formula ]:
C9H20ClNO2

[ Molecular Weight ]:
209.71400

[ Exact Mass ]:
209.11800

[ PSA ]:
29.46000

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22-36

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1(a)


Related Compounds