Quorum Sensing-IN-2

Names

[ CAS No. ]:
2925926-80-1

[ Name ]:
Quorum Sensing-IN-2

Biological Activity

[Description]:

Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum Sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum Sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Zhang P, et al. Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors. J Med Chem. 2023 Jul 13;66(13):8441-8463.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H13F2NO3

[ Molecular Weight ]:
341.31

Related Compounds

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