2925926-80-1

2925926-80-1 structure

Name: Quorum Sensing-IN-2
Chemical Name: Quorum Sensing-IN-2
CAS Number: 2925926-80-1
Molecular Formula: C₁₉H₁₃F₂NO₃
Molecular Weight: 341.31
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2023-09-25 18:58:37
Modify Date: 2024-02-14 17:40:25
Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum Sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum Sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1[1].

Name	Quorum Sensing-IN-2

Description	Quorum Sensing-IN-2 (compound 23e) is a quorum sensing inhibitor, which can reduce the pathogenicity of bacteria without affecting bacterial growth. Quorum Sensing-IN-2 inhibits bacterial infections with little hemolytic activity. Quorum Sensing-IN-2 shows synergistic effect with Ciprofloxacin (HY-B0356) in the bacteremia model infected with P. aeruginosa PAO1[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Zhang P, et al. Design and Synthesis of 4-Fluorophenyl-5-methylene-2(5H)-furanone Derivatives as Potent Quorum Sensing Inhibitors. J Med Chem. 2023 Jul 13;66(13):8441-8463.

Molecular Formula	C₁₉H₁₃F₂NO₃
Molecular Weight	341.31