MA220607

Names

[ Name ]:
MA220607

Biological Activity

[Description]:

MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA). MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

FtsZ[1]

[References]

[1]. Ma Y et al. New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes. Eur J Med Chem. 2023 Nov 7;263:115930.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₄H₃₈IN

[ Molecular Weight ]:
587.58

Related Compounds

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