2922826-56-8

2922826-56-8 structure

Name: MA220607
Chemical Name: MA220607
CAS Number: 2922826-56-8
Molecular Formula: C₃₄H₃₈IN
Molecular Weight: 587.58
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2024-02-27 16:50:55
Modify Date: 2025-08-25 17:02:51
MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA). MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively)[1].

Name	MA220607

Description	MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA). MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	FtsZ[1]
References	[1]. Ma Y et al. New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes. Eur J Med Chem. 2023 Nov 7;263:115930.

Molecular Formula	C₃₄H₃₈IN
Molecular Weight	587.58