Imnopitant

Names

[ Name ]:
Imnopitant

[Synonym ]:
3-Pyridinecarboxamide, N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-
N-[3,5-Bis(trifluoromethyl)benzyl]-N-methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)nicotinamide
N-[3,5-bis(trifluoromethyl)benzyl]-N-methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-3-carboxamide

Biological Activity

[Description]:

Imnopitant is a NK1 receptor antagonist (WO2020132716, compound 1) [1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor

[Target]

NK1

[In Vitro]

Imnopitant is a NK1 receptor antagonist[1].

[References]

[1]. WO2020132716

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
606.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₂₈F₆N₄O

[ Molecular Weight ]:
550.54

[ Flash Point ]:
320.6±31.5 °C

[ Exact Mass ]:
550.216736

[ LogP ]:
4.65

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.540

Related Compounds

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