Zinpyr-1
Names
[ CAS No. ]:
288574-78-7
[ Name ]:
Zinpyr-1
[Synonym ]:
2-(4,5-Bis{[bis(2-pyridinylmethyl)ammonio]methyl}-2,7-dichloro-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
3H-Xanthene-4,5-dimethanaminium, 9-(2-carboxyphenyl)-2,7-dichloro-6-hydroxy-3-oxo-N,N,N,N-tetrakis(2-pyridinylmethyl)-, bis(inner salt)
zinpyr-1
zp 1
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Boiling Point ]:
931.2±65.0 °C at 760 mmHg
[ Melting Point ]:
185-187ºC
[ Molecular Formula ]:
C46H36Cl2N6O5
[ Molecular Weight ]:
823.721
[ Flash Point ]:
517.0±34.3 °C
[ Exact Mass ]:
822.212402
[ PSA ]:
145.78000
[ LogP ]:
6.20
[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.745
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Syst. Biol. Reprod. Med. 61(1) , 18-25, (2014)
Several studies reported that chronic alcohol consumption alters the intestinal mucosa barrier, and subsequent entrance of endotoxins into the bloodstream. In many tissues endotoxin exposure causes th...
tert-Butylhydroquinone mobilizes intracellular-bound zinc to stabilize Nrf2 through inhibiting phosphatase activity.Am. J. Physiol. Cell Physiol. 309 , C148-58, (2015)
The nuclear factor erythroid 2-related factor 2 (Nrf2) is required to combat increases in oxidative stress. The chemical compound tert-butylhydroquinone (tBHQ) can downregulate Kelch-like ECH-associat...
Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.Neurobiol. Dis. 81 , 4-13, (2015)
The aim of this study was to investigate the role of the synaptic metabotropic zinc receptor mZnR/GPR39 in physiological adaptation to epileptic seizures. We previously demonstrated that synaptic acti...