FAAH-IN-8

Names

[ Name ]:
FAAH-IN-8

Biological Activity

[Description]:

FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 value of 6.7 nM and a Ki value of 5 nM. FAAH-IN-8 has high blood-brain permeability and a significant antioxidant profile with no neurotoxicity[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FAAH

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> FAAH

[References]

[1]. Shivani Jaiswal, et al. Lead optimization study on indoline-2,3-dione derivatives as potential fatty acid amide hydrolase inhibitors. J Biomol Struct Dyn. 2023, 41 19.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₄N₄O

[ Molecular Weight ]:
302.33

Related Compounds

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