2-Aminobenzophenone

Names

[ Name ]:
2-Aminobenzophenone

[Synonym ]:
2-BENZOYLANILINE
EINECS 220-613-9
o-Benzoylaniline
2-Aminobenzophenone
2-Aminophenyl phenyl ketone
Methanone, (2-aminophenyl)phenyl-
2-aminophenyl-phenylmethanone
2-Benzoylbenzenamine
(2-Aminophenyl)(phenyl)methanone
MFCD00007713
Benzophenone,2-amino
2-amino-benzophenone
ortho-aminobenzophenone
o-Aminobenzophenone

Biological Activity

[Description]:

2-Aminobenzophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

是有机合成、医药、农药和染料的重要原料和中间体。

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
383.7±25.0 °C at 760 mmHg

[ Melting Point ]:
103-107 °C(lit.)

[ Molecular Formula ]:
C₁₃H₁₁NO

[ Molecular Weight ]:
197.24

[ Flash Point ]:
185.9±23.2 °C

[ Exact Mass ]:
197.084061

[ PSA ]:
43.09000

[ LogP ]:
2.50

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.628

[ Water Solubility ]:
practically insoluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29223900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922399090

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.

PLoS ONE 9(5) , e95998, (2014)

Topoisomerase 1 inhibition is an important strategy in targeted cancer chemotherapy. The drugs currently in use acting on this enzyme belong to the family of the camptothecins, and suffer severe limit...

Effects of conformational restriction of 2-amino-3-benzoylthiophenes on A(1) adenosine receptor modulation.

J. Med. Chem. 53 , 6550-9, (2010)

2-Amino-3-benzoylthiophenes (2A3BTs) have been widely reported to act as allosteric enhancers (AEs) at the A(1) adenosine receptor (A(1)AR). Herein we describe the synthesis of a series of 1-aminoinde...