BAY-3153

Names

[ Name ]:
BAY-3153

Biological Activity

[Description]:

BAY-3153 is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM)[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CCR

Signaling Pathways >> Immunology/Inflammation >> CCR

Research Areas >> Inflammation/Immunology

[In Vivo]

BAY-3153 (10 mg/kg) treatment shows reduction of infiltrating macrophages in experimental renal ischemia/reperfusion model in mice[1].

[References]

[1]. https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/BAY-3153

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₉Cl₂N₃O₄

[ Molecular Weight ]:
506.42

Related Compounds

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