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BAY-524

Names

[ CAS No. ]:
1445830-39-6

[ Name ]:
BAY-524

Biological Activity

[Description]:

BAY-524 is a Bub1 inhibitor, with an IC50 of 450 nM for human Bub1 in the presence of 2 mM ATP.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[Target]

IC50: 450 nM (human Bub1, 2 mM ATP)[1]


[References]

[1]. Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C24H24F2N6O3

[ Molecular Weight ]:
482.48

Related Compounds