Cdc7-IN-12

Names

[ CAS No. ]:
2764865-33-8

[ Name ]:
Cdc7-IN-12

Biological Activity

[Description]:

Cdc7-IN-12 (compound 1) is a potent CDC7 inhibitor with an IC50 of <1 nM. Cdc7-IN-12 shows antiproliferative activities with IC50 of 100-1000 nM in COLO205 cells. Cdc7-IN-12 has the potential for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

Cdc7:<1 nM (IC50)


[References]

[1]. Huang XIanhai, et al. Heterocyclic pericondensed cdc7 kinase inhibitors for the treatment of cancer. WO2022055963A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H14N2O2S

[ Molecular Weight ]:
298.36

Related Compounds