Cdc7-IN-6
Names
[ CAS No. ]:
1402057-88-8
[ Name ]:
Cdc7-IN-6
Biological Activity
[Description]:
Cdc7-IN-6 (compound I-D) is a potent Cdc7 kinase inhibitor (IC50=4 nM), extracted from patent WO2019165473A1, compound I- D, has anti-tumor activity[1].
[Related Catalog]:
[In Vitro]
Cdc7-IN-6 demonstrates potent inhibitory activity (IC50<3 µΜ) in a range of solid tumor cell lines, including those of bladder (5673, RT1 12/84), sarcoma (143B, CADO-ES1, RD-ES, A673), colon and cecum (Colo-205, DLD-l, LS1034, SK-CO-l, SNU-C1), renal (U0.31), head-and-neck (CNE-2Z, RPMI-2650), melanoma (A2058, A875), and gastric (HGC-27) lineages[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C21H22F3N5O4
[ Molecular Weight ]:
465.43