SARS-CoV-2-IN-17

Names

[ CAS No. ]:
2761911-44-6

[ Name ]:
SARS-CoV-2-IN-17

Biological Activity

[Description]:

SARS-CoV-2-IN-17 (Compound 16) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-17 exhibits potent anti-viral activity with the EC50 of 2.18 μM. SARS-CoV-2-IN-17 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-17 is a potent NPro ligand[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Yi-Ting Wang, et al. Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2. Eur J Med Chem. 2022 Jan 5;227:113966.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₉F₃N₂O₃

[ Molecular Weight ]:
380.36

Related Compounds

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