2761911-44-6

2761911-44-6 structure

Name: SARS-CoV-2-IN-17
Chemical Name: SARS-CoV-2-IN-17
CAS Number: 2761911-44-6
Molecular Formula: C₁₉H₁₉F₃N₂O₃
Molecular Weight: 380.36
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2022-08-10 19:18:03
Modify Date: 2024-01-16 10:53:25
SARS-CoV-2-IN-17 (Compound 16) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-17 exhibits potent anti-viral activity with the EC50 of 2.18 μM. SARS-CoV-2-IN-17 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-17 is a potent NPro ligand[1].

Name	SARS-CoV-2-IN-17

Description	SARS-CoV-2-IN-17 (Compound 16) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-17 exhibits potent anti-viral activity with the EC50 of 2.18 μM. SARS-CoV-2-IN-17 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-17 is a potent NPro ligand[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
References	[1]. Yi-Ting Wang, et al. Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2. Eur J Med Chem. 2022 Jan 5;227:113966.

Molecular Formula	C₁₉H₁₉F₃N₂O₃
Molecular Weight	380.36