5-HT7 receptor ligand 1

Names

[ CAS No. ]:
2758571-64-9

[ Name ]:
5-HT7 receptor ligand 1

Biological Activity

[Description]:

5-HT7 receptor ligand 1 (Compound 5c) is a 5-HT7 receptor ligand with a Ki of 8 nM. 5-HT7 receptor ligand 1 is not hepatotoxic and exhibit moderate potential interaction with other drugs metabolized by CYP3A4 or CYP2D6[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT7 Receptor:8 nM (Ki)


[References]

[1]. Kułaga D, et al. Aminotriazines with indole motif as novel, 5-HT7 receptor ligands with atypical binding mode. Bioorg Chem. 2020 Nov;104:104254.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H23N7

[ Molecular Weight ]:
373.45

Related Compounds