(S)-GFB-12811

Names

[ Name ]:
(S)-GFB-12811

Biological Activity

[Description]:

(S)-GFB-12811 (compound 596) is a potent and selective CDK5 inhibitor, with an IC50 value less than 10 nM. (S)-GFB-12811 can be used in the research of cell cycle progression, neuronal development, tumorigenesis[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

Research Areas >> Neurological Disease

[Target]

CDK5:<10 nM (IC50)

CDK2:100 nM~1 μ nM (IC50)

[References]

[1]. Malojcic Goran, et al. Substituted 1,6-naphthyridines as inhibitors of CDK5 and their preparation. Patent WO2022011274.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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