KRAS G12C inhibitor 56

Names

[ Name ]:
KRAS G12C inhibitor 56

Biological Activity

[Description]:

KRAS G12C inhibitor 56 (compound IC-6) is a potent SOS1 inhibitor with an IC50 of 1.6 nM. KRAS G12C inhibitor 56 can be used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

IC50: 1.6 nM (SOS1)[1].

[References]

[1]. Jason ABBOTT, et al. Annulated 2-amino-3-cyano thiophenes and derivatives for the treatment of cancer. Patent WO2021245051A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₉N₇O₄S

[ Molecular Weight ]:
617.76

Related Compounds

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