KRAS G12C inhibitor 50

Names

[ CAS No. ]:
2760354-12-7

[ Name ]:
KRAS G12C inhibitor 50

Biological Activity

[Description]:

KRAS G12C inhibitor 50 (Example 4) is a KRAS G12C inhibitor with an IC50 of 46.7 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS(G12C):46.7 nM (IC50)


[References]

[1]. Guoliang Zhang, et al. Imidazotriazine and pyrrolopyrimidine derivatives as kras g12c inhibitors. WO2022028492A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H34N8O2

[ Molecular Weight ]:
550.65

Related Compounds