KRAS G12C inhibitor 52

Names

[ CAS No. ]:
2761204-87-7

[ Name ]:
KRAS G12C inhibitor 52

Biological Activity

[Description]:

KRAS G12C inhibitor 52 (Compound 7) is a KRAS G12C inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRAS(G12C)


[In Vitro]

KRAS G12C inhibitor 52 (Compound 7) inhibits proliferation of NCI-H358 cells with an IC50 of 67.2 nM[1].

[References]

[1]. Youxi CHEN, et al. Tetracyclic derivative, method for preparing same and use thereof in medicine. WO2022037630A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H32F2N8O3S

[ Molecular Weight ]:
670.73

Related Compounds