N-(4-(2-benzimidazolyl)phenyl)maleimide

Names

[ Name ]:
N-(4-(2-benzimidazolyl)phenyl)maleimide

[Synonym ]:
EINECS 248-173-3
N-[4-(2-benzimidazolyl)phenyl]-maleimide
1H-Pyrrole-2,5-dione, 1-[4-(1H-benzimidazol-2-yl)phenyl]-
N-[4-(1H-benzoimidazol-2-yl)-phenyl]-maleimide
1-[4-(1H-Benzimidazol-2-yl)phenyl]-1H-pyrrole-2,5-dione
MFCD00042767
BIPM
N-[p-(2-benzimidazolyl)phenyl]maleimide
N-<p-(2-Benzimidazolyl)phenyl>maleinimid
N-(4-(2-benzimidazolyl)phenyl)maleimide
N-[4-(2-Benzimidazolyl)phenyl]maleimide

Biological Activity

[Description]:

N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Tanaka F, et, al. Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde. Chem Commun (Camb). 2004 Aug 7;(15):1762-3.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
556.3±52.0 °C at 760 mmHg

[ Melting Point ]:
247ºC

[ Molecular Formula ]:
C₁₇H₁₁N₃O₂

[ Molecular Weight ]:
289.288

[ Flash Point ]:
290.3±30.7 °C

[ Exact Mass ]:
289.085114

[ PSA ]:
66.06000

[ LogP ]:
2.12

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.742

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS03, GHS05, GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H272-H301-H312-H314-H317-H330-H334-H340-H350-H360FD-H372-H410

[ Precautionary Statements ]:
P201-P210-P260-P284-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P308 + P313-P403 + P233

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
UN3086 - class 6.1 - PG 1 - PIH - RQ - Toxic solids, oxidizing, n.o.s., HI: all

[ RTECS ]:
HX7750000

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Conformational change accompanying formation of oligomycin-induced Na(+)-bound forms and their conversion to ADP-sensitive phosphoenzymes in Na+,K(+)-ATPase.

J. Biochem. 109(2) , 299-306, (1991)

Oligomycin reduced the fluorescence intensity of an N-(p-(2-benzimidazoly)phenyl) maleimide (BIPM) probe at Cys-964 of the alpha-chain of pig kidney Na+,K(+)-ATPase with increase in the concentration ...

Different susceptibility to phospholipase A2 treatment of the fluorescence intensity changes in the vicinity of Cys-964 and Lys-501 in the alpha-chain of probe-labeled Na+,K(+)-ATPase.

J. Biochem. 115(3) , 454-62, (1994)

Phospholipase A2 [EC 3.1.1.4] treatment of pig kidney Na+,K(+)-ATPase [EC 3.6.1.3] labeled with fluorescence probes at the alpha-chain reduced the extent of the fluorescence intensity change of an N-[...

ATP-induced dynamic fluorescence changes of a N-[p-(2-benzimidazolyl)phenyl]maleimide probe at Cys241 in the alpha-chain of pig stomach H+,K+-ATPase.

J. Biochem. 122(3) , 659-65, (1997)

H+,K+-ATPase preparations from pig stomach were modified with a sulfhydryl fluorescence reagent, N-[p-(2-benzimidazolyl)phenyl] maleimide (BIPM). The addition of ATP to the modified enzyme preparation...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.