FabH-IN-1

Names

[ Name ]:
FabH-IN-1

Biological Activity

[Description]:

FabH-IN-1 (compound 3f) is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broad-spectrum antimicrobial target. FabH-IN-1 is effective against gram-positive and gram-negative. FabH-IN-1 is also a good antioxidant[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme[1]

[References]

[1]. Ahmad H, et, al. A combine approach of chemical synthesis, biological evaluation and structural dynamics studies revealed thiazole substituted arylamine derivatives as potent FabH enzyme inhibitors. Bioorg Chem. 2020 Dec;105:104426.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₆N₂OS

[ Molecular Weight ]:
296.39

Related Compounds

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