2’-Deoxy-3’,2-anhydrouridine

Names

[ CAS No. ]:
26922-44-1

[ Name ]:
2’-Deoxy-3’,2-anhydrouridine

[Synonym ]:
threo-2,3'-anhydro-2'-deoxy-uridine

Biological Activity

[Description]:

2’-Deoxy-3’,2-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C9H10N2O4

[ Molecular Weight ]:
210.19

[ Exact Mass ]:
210.06400

[ PSA ]:
73.58000

Precursor & DownStream

Precursor

DownStream