<Suppliers Price>

2-Methyl-4-Isothiazolin-3-one

Names

[ CAS No. ]:
2682-20-4

[ Name ]:
2-Methyl-4-Isothiazolin-3-one

[Synonym ]:
METHYLISOTHIAZOLIN
2-Methyl-3(2H)-isothiazolone
2-METHYLISOTHIAZOLINONE
METHYLISOTHIAZOLINE
2-methylisothiazolin-3-one
MFCD00013254
2-Methyl-1,2-thiazol-3(2H)-one
METHYLISOTHIAZDINONE
Skycide 100
KATHONCG
methylisothiazolin-3-one
2-Methylisothiazol-3(2H)-one
Isothiazolone,2-methyl
N-Methylisothiazolone
MI
2-methyl-3-isothiazolone
2-methyl-2H-isothiazol-3-one
2-Methyl-4-Isothiazolin-3-one
3(2H)-Isothiazolone, 2-methyl-
methylisothiazolinone
2-methylisothiazolone
T5SNVJ B1
METHYLISOTHIAZOLONE
EINECS 220-239-6
N-methyl-isothiazole-HCl
MIT
2-Methyl-4-isothiazoline-3-one

Biological Activity

[Description]:

Methylisothiazolinone is a synthetic biocide and preservative that can be widely used in both industrial and consumer products. Methylisothiazolinone as a preservative in cosmetic and toiletrie products[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Mari Paz Castanedo-Tardana, et al. Methylisothiazolinone. Dermatitis. Jan-Feb 2013;24(1):2-6.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
182.8±23.0 °C at 760 mmHg

[ Melting Point ]:
254-256 °C(lit.)

[ Molecular Formula ]:
C4H5NOS

[ Molecular Weight ]:
115.154

[ Flash Point ]:
64.3±22.6 °C

[ Exact Mass ]:
115.009186

[ PSA ]:
50.24000

[ LogP ]:
0.05

[ Vapour Pressure ]:
0.8±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.589

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX8157080
CHEMICAL NAME :
3(2H)-Isothiazolone, 2-methyl-
CAS REGISTRY NUMBER :
2682-20-4
LAST UPDATED :
199710

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314-H317-H331-H335-H400

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R20/21/22;R34;R43;R50

[ Safety Phrases ]:
S60-S61-S36/37/39-S26-S24-S45

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
FE1250000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2934100090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Methylisothiazolinone contact allergy and dose-response relationships.

Contact Dermatitis 64(6) , 330-6, (2011)

Methylisothiazolinone (MI) used alone is a new preservative causing a high prevalence of contact allergy. The eliciting threshold of MI is unknown. The combination of MI and phenoxyethanol enhances th...

Follow-up of the monitored levels of preservative sensitivity in Europe: overview of the years 2001-2008.

Contact Dermatitis 67(5) , 312-4, (2012)

Occupational contact dermatitis in painters: an analysis of patch test data from the Danish Contact Dermatitis Group.

Contact Dermatitis 67(5) , 293-7, (2012)

Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation.To characterize painters with contact ...


More Articles


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.