3’-Deoxy-3’-fluoro-xylocytidine

Names

[ CAS No. ]:
26563-01-9

[ Name ]:
3’-Deoxy-3’-fluoro-xylocytidine

[Synonym ]:
4-Amino-1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 4-amino-1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)-

Biological Activity

[Description]:

3’-Deoxy-3’-fluoro-xylocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
500.1±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C9H12FN3O4

[ Molecular Weight ]:
245.21

[ Flash Point ]:
256.2±32.9 °C

[ Exact Mass ]:
245.081177

[ LogP ]:
-1.14

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.697

Related Compounds