Axl-IN-5

Names

[ CAS No. ]:
2642224-24-4

[ Name ]:
Axl-IN-5

Biological Activity

[Description]:

Axl-IN-5 (compound 1) is a AXL inhibitor with an IC50 of 283 nM. Axl-IN-5 has anticancer effects[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> TAM Receptor

[Target]

IC50: 283 nM (AXL)[1]


[References]

[1]. Lin-Lin Zhang, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H35N5O2S

[ Molecular Weight ]:
541.71


Related Compounds